Association of Circulating Chemerin Levels and Arterial Stiffness

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01293929

Enrollment

120

Registered

2011-02-11

Start date

2011-02-28

Completion date

2011-03-31

Last updated

2011-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerosis, Obesity

Brief summary

Chemerin is a novel adipokine that might provide a link between chronic inflammation and obesity. Pulse wave velocity(PWV) is a useful method for examining arterial stiffness, meaning early-stage atherosclerosis. Therefore, in the present study, the investigators examined the relationship between circulating chemerin and arterial stiffness measured using PWV in obese persons.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Self referred persons for visiting routine medical check in our clinic

Exclusion criteria

* Malignancy * Severe renal or hepatic disease

Design outcomes

Primary

Measure	Time frame	Description
The difference of serum chemerin level between obese and non-obese groups	at the time of initial enrollment (4weeks)	serum chemerin levels of all participants were by determined by an enzyme-linked immunosorbent assay (ELISA) kit (Biovender Laboratory Medicine Inc., Modrice, Czech Republic)

Secondary

Measure	Time frame	Description
The correlation of serum chemerin levels with arterial stiffness	at the time of enrollment (4 weeks)	Arterial stiffness was measure using a Colin Waveform Analyser (model BP-203RPE II; Colin, Komaki, Japan). It was expressed as branchial ankle pulswe wave velocity (baPWV)

Countries

South Korea

Contacts

Primary ContactHye Jin Yoo

deisy21@naver.com82226263045

Outcome results