Skin Sterility After Use of Ethyl-chloride Spray.
Conditions
Keywords
Topical, Skin, sterility, ethylchloride, ethyl, chloride, spray
Brief summary
The aim of this study is to investigate sterility of ethyl-chloride topical anesthetic spray when used prior to an injection. The hypothesis is that the spray does not change the sterility of the injection site after skin is prepped.
Detailed description
This is an IRB-approved, prospective, blinded, controlled study. In the first set of experiments, skin sterility is assessed. Healthy adult subjects are prepared for mock injections of shoulders and knees. No injection is performed. Each site has a set of 3 skin cultures: 1) prior to the alcohol prep (pre-prep), 2) post-alcohol prep (pre-spray), and 3) after ethyl-chloride was sprayed on the site (post-spray). In the second set of experiments, sterility of ethyl chloride is tested directly by culturing the liquid from the spray bottles.
Interventions
None listed
Sponsors
University of Medicine and Dentistry of New Jersey
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
* age -- 18-85 * healthy skin at shoulder and knee area
Exclusion criteria
* allergy to ethyl-chloride * skin lesions at shoulder or knee
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| culture positivity | 5 days | Cultures before and after Ethyl-Chloride spray are compared to see if there is any difference. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Native skin flora | 5days | Cultures of skin prior to skin prep are taken to define to native flora at the shoulder and knee area. |
Countries
United States
Outcome results
None listed