HIV
Conditions
Keywords
HIV, Medication adherence, computer-based intervention
Brief summary
The purpose of this study is to develop and examine the feasibility and initial efficacy of a computer-based intervention to improve medication adherence among people living with HIV.
Interventions
BEHAVIORALLife Steps for Medication Adherence
The intervention was adapted into an electronic version of the empirically supported Life Steps intervention for HIV medication adherence. Education about HIV and medication adherence, motivational interviewing, cognitive behavioral techniques, and problem-solving strategies to improve medication adherence and clinical outcomes in people living with HIV were also included in the intervention.
Sponsors
Oklahoma State University Center for Health Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* infected with HIV * over age 18 * currently prescribed a Highly Active Antiretroviral Therapy (HAART) regimen * prescribed a regimen for the first time, changing regimens, or report adherence below 95% agree to brief follow-up interviews
Exclusion criteria
* physical impairment that would prevent them from successfully completing the computer-based program (e.g., blind, deaf, severe neuropsychological impairment) * Actively psychotic * Not fluent in English
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HIV medication adherence | up to 6 months | Self-reported adherence to HIV medications will be assessed using the AACTG Medication Adherence Questionnaire (M. A. Chesney, et al., 2000). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| HIV Treatment Adherence Self-Efficacy | Baseline, 1-month, 3 months, and 6-months | Self-efficacy for adherence to HIV medications will be assessed using the HIV-ASES (Johnson et al., 2007). The HIV-ASES is a 12-item scale of patient confidence in their ability to carry out behaviors related to adhering to medication regimens. Responses range from 1 (cannot do it at all) to 10 (completely certain can do it). Item scores are averaged with higher scores indicating higher adherence self-efficacy. |
| Quality of Life | Baseline, 1-month, 3-months, and 6-months | Quality of life will be assessed using the McGill Quality of Life questionnaire (S. Robin Cohen, Hassan, Lapointe, & Mount, 1996). This instrument is a 16-item scale that assesses quality of life in four domains: physical well-being, psychological well-being, existential well-being, and support; each item is assessed on a 0-10 point scale. |
| Viral Load | Baseline, 1 month, 3 months, and 6 months | — |
| CD4 cell count | Baseline, 1 month, 3 months, and 6 months | — |
Countries
United States
Outcome results
None listed