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Dosage-dependence of Graded Exercise Therapy in Patients With Patellofemoral Pain Syndrome.

Dosage-dependence of Graded Exercise Therapy in Patients With Patellofemoral Pain Syndrome. A Randomized Controlled Clinical Trial.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01290705
Enrollment
40
Registered
2011-02-07
Start date
2007-11-30
Completion date
2010-12-31
Last updated
2016-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellofemoral Pain Syndrome

Keywords

Knee, Anterior Cruciate Ligament, Pain, Patella, Exercise Therapy

Brief summary

With this study two different therapeutic exercise regimens will be compared in patients with anterior knee pain (patellofemoral pain syndrome, PFPS).

Detailed description

Exercise therapy is widely used in the conservative treatment of patellofemoral pain syndrome (PFPS), but there is still no consensus on recommending any specific rehabilitation program. This study evaluates two different therapeutic exercise regimens in patients with PFPS and their effect on pain at rest and function. Supervised exercise therapy will be applied in both groups three times a week over a 3-month period with individually tailored and graded exercise programs, differing between groups in terms of number of exercises, number of repetitions and sets, and time spent on performing aerobic exercises.

Interventions

BEHAVIORALHigh exercise therapy
BEHAVIORALLow exercise therapy

Sponsors

Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
16 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

Presence of at least 3 symptoms of the following: Pain when * Walking stairs * Squatting * Running * Cycling * Sitting with knees flexed for a prolonged period of time * Grinding of the patella * Other positive physical tests (Clarke's test, patellar crepitus, tenderness upon palpation of the posterior surface of the patella, patellar facets or surrounding structures)

Exclusion criteria

* Knee osteoarthrosis/ arthritis * previous knee injury or knee operations * patellar tendinopathy * Osgood- Schlatter's disease * Other defined pathological conditions of the knee

Design outcomes

Primary

MeasureTime frameDescription
Pain measured by a Visual analogue scale (VAS).Pre-test, post-test (after completed intervention at 3 months) and one year follow-up.This scale was illustrated with a 100 mm horizontal line with descriptors no pain at the 0 mm mark and worst pain imaginable anchoring the 100 mm. Participants were required to place a vertical mark on the horizontal line, representing their average level of pain experienced during the last 24 hours. This was done at rest and provided an illustration of the perceived pain severity, rated in millimetres.

Secondary

MeasureTime frame
Function measured by a Step-down test and by a modified Functional Index Questionnaire (FIQ).Pre-test, post-test (at 3 months after completed intervention) and at one year follow-up.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 23, 2026