Infant, Newborn Diseases
Conditions
Keywords
Glucose, analgesic, newborns
Brief summary
Glucose has analgesic and calming effects in newborns. To date, it is not known whether the beneficial effects extend to care giving procedures that are performed after painful procedures. The investigators objective is to determine the effect of glucose 25% analgesia for procedural pain on infant pain responses during a subsequent care giving procedure.
Detailed description
Pain in the newborn and young infant is a source of stress for the infant, family and care providers. During hospitalization, a neonate undergoes a number of necessary procedures that may be either painful or cause discomfort to the baby. Pain experienced during the neonatal period is known to have long term effects on the baby. The red-reflex test is a routine examination performed on a neonate after birth and once again before discharge from the hospital. The examination causes discomfort to the infant. Glucose has analgesic and calming effects in newborns. To date, it is not known whether the beneficial effects extend to care giving procedures that are performed after painful procedures. Our objective is to determine the effect of glucose 25% analgesia for procedural pain on infant pain responses during a subsequent care giving procedure.
Interventions
DRUGGlucose 25%
1ml of glucose 25% once
Sponsors
The Baruch Padeh Medical Center, Poriya
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
DOUBLE (Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
1 Days to 16 Days
Healthy volunteers
Yes
Inclusion criteria
* Full term above 37 weeks gestation. * Normal birth-weight, healthy infants * Males and Females * Whose parents have signed the informed consent form
Exclusion criteria
* Premature born below 37 weeks * Chromosomal abnormalities or congenital malformation. * Suffering neurological imbalance * Inability of oral feeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reduced infant response to a routine care procedure after glucose 25% analgesia | 30 minutes | An observer nurse will focus on the infant's facial expression. A score between 0 and 3 will be assigned for each of the three facial expression indicators. For physiological data, infants will be monitored for changes in heart rate and oxygen saturation using a transcutaneous pulse oximeter. A score between 0 and 3 will be assigned for each of the physiological indicators |
Outcome results
None listed