Heart Failure With Preserved Ejection Fraction
Conditions
Keywords
heart failure, preserved ejection fraction
Brief summary
The purpose of this study is to determine whether exercise training will improve functional capacity in patients with heart failure and preserved ejection fraction.
Interventions
BEHAVIORALExercise training
Exercise training program for 3 months (two times a week).
Sponsors
Clalit Health Services
Hadassah Medical Organization
Meir Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Clinical heart failure * Preserved ejection fraction (\>50%) * Stable clinically * New York Heart Association Class II-III
Exclusion criteria
* Unable to exercise * Other debilitating or unstable disease limiting length of life * Implanted pacemaker
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline of peak oxygen uptake on graded exercise. | After 3 month exercise training | Changes in physical fitness after 3 month exercise training. This will be measured by a cardiopulmonary exercise test with recording of maximal oxygen uptake during incremental exercise. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline of six minute walk | After 3 month exercise training | Change in the distance covered during a 6 minute walk after 3 month exercise training. |
| Change from baseline of NYHA class | After 3 month exercise training | Change in subjective assessment of function capacity based on the New York Heart Association Class classification after 3 month exercise training. |
Countries
Israel
Contacts
Primary ContactMeirav Miara, MA
Outcome results
None listed