Efficacy Study of a Low Volume of Water Intake and Mosapride for Endoscopy in Patients With Subtotal Gastrectomy

Efficacy of a Low Volume of Water Intake and Mosapride for Endoscopy Preparation in Gastric Cancer Patients With Subtotal Gastrectomy: A Randomized Controlled Trial

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01284764

Acronym

SMW

Enrollment

144

Registered

2011-01-27

Start date

2011-01-31

Completion date

2011-09-30

Last updated

2011-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Foreign Body Left During Endoscopic Examination

Keywords

Endoscopy, Gastrectomy, Stomach neoplasms

Brief summary

A low volume of water intake and mosapride will effectively reduce food residue in remnant stomach for patients who had undergone subtotal gastrectomy due to gastric cancer.

Detailed description

We evaluate that a 500mL of water intake and mosapride will effectively reduce food residue in remnant stomach for patients who had undergone subtotal gastrectomy due to gastric cancer. We plan to compare this method with routine midnight fasting method for endoscopy in patients with subtotal gastrectomy.

Interventions

DRUGMosapride

Mosapride 10mg, one dosage, once evening of the day before the endoscopy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Outpatients who had subtotal gastrectomy for gastric cancer

Exclusion criteria

* Pregnancy * Lactation * History of anastomotic stricture * Recurrent advanced gastric cancer * Poor general condition( \> 2 ECOG) * Other disseminated malignancy * Significant renal failure or congestive heart failure (CHF) * Liver failure

Design outcomes

Primary

Measure	Time frame	Description
Degrees of food residue using endoscopic scoring system	six months	We plan to evaluate how much a low volume of water and mosapride, compared with routine fasting, reduse food residue in gastric remnant for endoscopy.

Secondary

Measure	Time frame	Description
Tolerability of a low volume of water and mosapride	six months	We plan to evaluate tolerability of a low volume of water and mosapride compared with routine fasting for endoscopy preparation in patients with subtotal gastrectomy

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026