Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma

Effect of Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% in the Treatment of Ocular Surface Disease in Glaucoma Patients

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01284439

Enrollment

120

Registered

2011-01-27

Start date

2011-01-31

Completion date

2012-02-29

Last updated

2011-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular Surface Disease, Glaucoma

Brief summary

To study effect of hydroxypropylmethylcellulose 0.3% and sodium hyaluronate 0.18% in the treatment of ocular surface disease in glaucoma patients.

Interventions

DRUGhydroxypropylmethylcellulose

TearA: QID to every 2 hous , 1-2 drops per each time , duration 1 month

DRUGsodium hyaluronate

QID to every 2 hous, 1-2 drops per each time, duration 1 month

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* OSDI \> or equal 20 and eye lid inflammation , meibomian gland inflammation,conjunctival injection,follicle at tarsus , positive corneal staining , tear break up time less than 8 seconds , tear volume less than 5.5 mm.

Exclusion criteria

* Age below 18 yo * Active infectious corneal disease * Post penetrating keratoplasty or glaucoma drainage device * Known allergy to medication * Lactation , Pregnant

Design outcomes

Primary

Measure	Time frame
Ocular surface index score	1 month

Secondary

Measure	Time frame
Eye lid inflammation, corneal staining score, tear break up time and tear volume	1 month

Countries

Thailand

Contacts

Primary ContactAssocProf Pinnita Tanthuvanit

02-4198036

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026