Renal Tubular Acidosis in Incident Renal Transplant Recipients

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01283880

Enrollment

Registered

2011-01-26

Start date

2012-05-31

Completion date

2013-06-30

Last updated

2012-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Transplant Disorder

Keywords

kidney, transplantation, metabolic acidosis, renal tubular acidosis, nephrocalcinosis

Brief summary

Metabolic acidosis is a common complication in incident renal transplant recipients. Protracted acidosis may be associated with osteoporosis, inflammation, negative protein balance and malnutrition, and last but not least may cause renal dysfunction. Preliminary data indicate an increased prevalence of nephrocalcinosis in renal transplant biopsies of incident patients presenting with metabolic acidosis. The present study aims (1)evaluate the prevalence and type of renal tubular acidosis (RTA) in incident renal transplant recipients and to identify clinical correlates and (2) to find associations between RTA, nephrolithiasis and nephrocalcinosis

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Recipient of a single kidney transplant included in the protocol biopsy program. * eGFR \> 30 ml/min * Age ≥ 18 years * Written informed consent

Exclusion criteria

* none

Countries

Belgium

Contacts

Primary ContactPieter Evenepoel, MD

pieter.evenepoel@uz.kuleuven.ac.be003216344580

Outcome results