Hydrogen Sulfide Detoxification and Butyrate Metabolism in Ulcerative Colitis

Impact of the Mucosal Detoxification Mechanism of Hydrogen Sulphide on the Oxidation Pathway of Butyrate in Ulcerative Colitis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01282905

Enrollment

106

Registered

2011-01-25

Start date

2008-10-31

Completion date

2010-12-31

Last updated

2011-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative Colitis

Brief summary

The purpose of this study is to evaluate the relation between sulphide detoxification and butyrate metabolism at the level of gene expression and enzyme activity in ulcerative colitis patients and healthy controls.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

\- Ulcerative colitis patients: patients diagnosed with ulcerative colitis

Exclusion criteria

* Healthy controls: no diagnosis of inflammatory bowel diseases * Intake of antibiotics in the last month before the study

Countries

Belgium

Outcome results