Weaning Period
Conditions
Brief summary
Non-invasive ventilation (NIV) has been proposed to reduce the incidence of ventilatory dysfunction following mechanical ventilation weaning. However, the nasogastric tube reduces the airtightness of the facial mask used to perform non-invasive ventilation and induces air leaks. The presence of leaks at the patient-mask interface can increase the risk of patient-ventilator asynchrony, which in turn leads to increase patient discomfort. Neurally adjusted ventilatory assist (NAVA)could contribute to decreasing asynchrony. Its principle is to record the diaphragmatic electrical activity and to control the ventilator. The investigators hypothesized driving the ventilator based on a neural signal (diaphragm electrical activity) would reduce patient-ventilator asynchronies in NIV
Interventions
OTHERDevice: Neurally Adjusted Ventilatory Assistance
Device: Neurally Adjusted Ventilatory Assistance In ICU following extubation NIV was performed as follows: facial mask with PSV/NIV mode to define settings for NAVA ventilation facial use with NAVA/NIV mode
Sponsors
Pierre and Marie Curie University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
Patients with increased risk of post-extubation ventilatory dysfunction following invasive mechanical ventilation weaning.
Exclusion criteria
* Contra-indication to non-invasive ventilation * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Triggering delay | Every inspiration, for 10 minutes | Duration between the onset of neural inspiration and the onset of insufflation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cycling off delay | Every inspiration, for 10 minutes | Delay between the end of neural inspiration and the end of insufflation |
Countries
France
Outcome results
None listed