Endometrial Biopsy Protocol for In Vitro Fertilization (IVF)

Comparing Timing and Number of Endometrial Biopsies in IVF Treatment and Identifying Biochemical Markers to Predict Endometrial Receptivity

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01278706

Enrollment

200

Registered

2011-01-19

Start date

2011-01-31

Completion date

Unknown

Last updated

2011-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility, Recurrent Implantation Failure

Brief summary

Endometrial biopsy has been shown to improve IVF pregnancy and live birth rates. The optimal time of performing the biopsy is yet to be established. In this study, the investigators will compare different temporal timing of the biopsies with regards to the menstrual cycle and their affect on the success rates of the treatment.

Interventions

PROCEDUREendometrial biopsy/ies

performing office endometrial biopsy with a disposable sterile catheter

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 38 Years

Healthy volunteers

Yes

Inclusion criteria

* normal menstrual cycle * between 1-6 previous failed IVF cycles * normal hormonal profile

Exclusion criteria

* intrauterine procedure in last 3 months * hydrosalpinx * intrauterine lesion /malformation

Design outcomes

Primary

Measure	Time frame
pregnancy rates	2 years

Secondary

Measure	Time frame
live birth rates	3 years

Countries

Israel

Contacts

Primary ContactDan Levin, M.D.

dan_l@clalit.org.il+972-89441623

Backup ContactIrit Granot, Ph.D.

irit_g@clalit.org.il+972-8-9441623

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026