Pancreatic Neoplasm
Conditions
Keywords
pancreas, pancreaticoduodenectomy, major complications
Brief summary
Pancreaticoduodenectomy (PD) still carries a high rate of severe postoperative complications. No score is currently available to help identify the patient's surgical risk. The purpose of this study was to develop and validate a prognostic score to predict major postoperative complications after PD.
Detailed description
The investigators prospectively collected in an electronic database preoperative, intraoperative and outcome data of 700 patients undergoing PD in our Institution from 2002 to 2010. The investigators used a multivariate logistic regression analysis to create a new score to predict severe complications defined as Clavien-Dindo classification III, IV and V. The score was developed using a random two-thirds of the population (469 patients), and was then validated and calibrated in the remaining third of the patients (231).
Interventions
PROCEDUREPancreaticoduodenectomy
Resection of pancreatic lesion
Sponsors
Università Vita-Salute San Raffaele
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
\- Patients undergoing pancreaticoduodenectomy in our Institution
Exclusion criteria
* Metastatic disease * Patient not suitable for surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major Complication rate | Postoperative. Until 30 days after discharge | Clavien-Dindo grade III to V complications considered as major |
Countries
Italy
Outcome results
None listed