Treatment Response Evaluation in Gastrointestinal Stromal Tumor (GIST) Patients

Treatment Response Evaluation in Patients With Gastrointestinal Stromal Tumor Using PET/CT and DW MRI

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01276483

Enrollment

Registered

2011-01-13

Start date

2011-02-28

Completion date

2017-06-21

Last updated

2017-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal Tract, Soft Tissue Neoplasms

Keywords

GIST, Response Monitoring, Functional Magnetic Imaging, Positron Emission Tomography, Computer Tomography

Brief summary

The purpose of this study is to compare sensitivity, specificity and accuracy of PET, DW MRI and CT separately and combined for the evaluation of treatment response and progression-free survival in patients with GIST.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Metastatic GIST patients suitable for TKI treatment * GIST patients pursuing preoperative neoadjuvant TKI treatment

Exclusion criteria

* Patients with contraindications to MRI and/or TKI treatment. For patients with renal failure, CT without intravenous contrast will be performed according to clinical practice. * Patients who do not sign the consent paper for any reason or do not accept the study premises or patients who wish to withdraw for any reason during the study

Design outcomes

Primary

Measure	Time frame
Radiologic-pathologic correlation	2 years

Countries

Norway

Outcome results