Anesthesia
Conditions
Brief summary
Radial arterial cannulation is a common invasive procedure for real-time measurement of arterial blood pressure. Placement of the arterial catheter using conventional palpation is often relatively easy and quick, but this is not always true. A relatively new method for direct visualization of the artery is the use of two-dimensional ultrasound. This technique allows cannulation of the artery to take place under real-time visualization and may increase the success rate of first time pass of the needle. Another technique utilizing Doppler has also proven to be effective in cannulating the radial artery. This technique utilizes changes in acoustic pitch as the probe passes directly over the artery. The primary objective of this study is to compare the first attempt success rate for radial artery cannulation among the palpation, Doppler and U/S guided technique when applied by trainees. Secondary outcomes include: success rate within 5 minutes, successful, number of attempts required, and correlation between success rate and operator experience for successful cannulation of the radial artery.
Detailed description
Radial artery cannulation is a common invasive procedure in the operating room, intensive care unit and emergency department. It allows continuous hemodynamic monitoring and repeated arterial blood sampling. Although severe complications are rare, successful radial artery cannulation can be technically challenging, particularly in hypotensive patients and those with vascular disease. Multiple unsuccessful attempts at arterial cannulation increase patient discomfort, delay timely care and may also contribute to adverse events such as arterial spasm or local hematoma. The radial artery is traditionally located by palpation. A number of techniques to aid radial artery localization have been described. Doppler-assisted radial arterial cannulation was first described in 1976. Several case reports suggest that Doppler can be helpful in patients with difficult arterial access. More recently, ultrasound-guided radial artery cannulation has been described. In a recent meta-analysis of four randomized controlled trials, ultrasound increased the rate of cannulation on the first attempt by 71% compared with palpation. However, two of the studies were of children and all four were small, with 30-152 participants (311 in total), making the generalizability of these results to adult patients uncertain. Furthermore, variation in the training and experience of the operators was evident within one of the studies. Accordingly, the aim of this study is to compare three different radial arterial cannulation techniques in adult surgical patients when performed by anesthesia residents: Doppler; palpation; and ultrasound. We think that ultrasound would have a higher rate of cannulation on the first attempt compared with other techniques.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* Main OR patients at UIHC who require arterial catheter placement for surgery
Exclusion criteria
* The patients who will be excluded from the study include those who have had arterial cannulation in the previous month, infections at site of insertion, and AV shunts in upper extremity.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| First Attempt Success Rate With 3 Different Technique | 5 minutes | The primary objective of this study is to compare the first attempt success rate for radial artery cannulation between the palpation, Doppler and U/S guided technique when applied by anesthesia trainees. Secondary outcomes include: success rate within 5 minutes, time to successful cannulation compared with three different techniques. |
Secondary
| Measure | Time frame |
|---|---|
| Time to Successful Cannulation | 5 minutes |
| Total Success Rate | 5 min |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Ultrasound Participants will place arterial line using ultrasound technique
Ultrasound: Participants will place arterial line using ultrasound technique | 249 |
| Doppler Participants will place arterial line using doppler technique
Doppler: Participants will place arterial line using doppler technique | 244 |
| Palpation Participants will place arterial line using palpation technique
Palpation: Participants will place arterial line using Palpation technique | 256 |
| Total | 749 |
Baseline characteristics
| Characteristic | Doppler | Palpation | Ultrasound | Total |
|---|---|---|---|---|
| Age, Categorical <=18 years | 0 Participants | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical >=65 years | 100 Participants | 99 Participants | 101 Participants | 300 Participants |
| Age, Categorical Between 18 and 65 years | 144 Participants | 157 Participants | 148 Participants | 449 Participants |
| Age, Continuous | 61 years | 59 years | 60 years | 60 years |
| Region of Enrollment United States | 244 participants | 256 participants | 249 participants | 749 participants |
| Sex: Female, Male Female | 107 Participants | 106 Participants | 106 Participants | 319 Participants |
| Sex: Female, Male Male | 137 Participants | 150 Participants | 143 Participants | 430 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk | EG002 affected / at risk |
|---|---|---|---|
| deaths Total, all-cause mortality | — / — | — / — | — / — |
| other Total, other adverse events | 27 / 249 | 22 / 244 | 29 / 256 |
| serious Total, serious adverse events | 0 / 249 | 0 / 244 | 0 / 256 |
Outcome results
First Attempt Success Rate With 3 Different Technique
The primary objective of this study is to compare the first attempt success rate for radial artery cannulation between the palpation, Doppler and U/S guided technique when applied by anesthesia trainees. Secondary outcomes include: success rate within 5 minutes, time to successful cannulation compared with three different techniques.
Time frame: 5 minutes
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Ultrasound | First Attempt Success Rate With 3 Different Technique | 132 participants |
| Doppler | First Attempt Success Rate With 3 Different Technique | 101 participants |
| Palpation | First Attempt Success Rate With 3 Different Technique | 96 participants |
Time to Successful Cannulation
Time frame: 5 minutes
| Arm | Measure | Value (MEDIAN) |
|---|---|---|
| Ultrasound | Time to Successful Cannulation | 32 min |
| Doppler | Time to Successful Cannulation | 118 min |
| Palpation | Time to Successful Cannulation | 91 min |
Total Success Rate
Time frame: 5 min
Population: chi-squre test
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Ultrasound | Total Success Rate | 170 Participants |
| Doppler | Total Success Rate | 147 Participants |
| Palpation | Total Success Rate | 160 Participants |