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Impact of Genetic Polymorphisms on Dental Implant Loss

A Case-control Study on the Impact of Genetic Polymorphisms on Dental Implant Loss.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01274442
Acronym
Polymorphism
Enrollment
13
Registered
2011-01-11
Start date
2011-06-01
Completion date
2013-08-05
Last updated
2022-12-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients Treated by Means of 1 or More Dental Implants

Keywords

dental implant

Brief summary

Patients that may participate in this case-control study underwent dental implant surgery in the University Hospital in Ghent in 2004-2007. According to one of our recent papers based on this patient group, 34/461 patients lost one or more implants. The goal is to invite these 34 patients, to update the anamnesis, to perform a brief clinical oral examination and to have a blood sample. The latter is necessary to identify relevant genetic polymorphisms of the patient that are associated with implant loss. Among the remaining patients that did not lose implants, another 34 'controls' will be invited for the same examinations.

Interventions

To update the anamnesis.

A brief clinical oral examination will be performed.

PROCEDUREBlood sample

A blood sample will be taken to identify relevant genetic polymorphisms.

Sponsors

University Hospital, Ghent
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Dental implant surgery in the University Hospital in Ghent in 2004-2007. * Case: dental implant loss * Control: no dental implant loss

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
genetic polymorphisms associated with implant lossafter 3 to 6 yearsIdentification of genetic polymorphisms that are associated with implant loss. It concerns only one evaluation (1 blood sample).

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026