Exercise, Inflammation, Risk Factors Cardiovascular Disease, Sedentary Life
Conditions
Keywords
inflammation, lipids, CRP
Brief summary
About 32 healthy subjects are subjected to 4 weeks of exercise, 4 weeks of washout and 4 weeks of sedentary life style, randomization decides whether they start with exercise or with being couch potatoes. All participants are also randomized to also consume 150 g of blueberries on exercise days or not. The exercise is constituted of 5 km running 5 days a week during the 4 week period. The exercise period and the couch period are started and ended with a 5 km run at maximal speed and the fasting blood samples for cardiovascular risk factors are measured before and after this run, ie 8 times in total.
Interventions
BIOLOGICALBlueberries
150 grams of frozen blueberries on the same day as exercise
Sponsors
University Hospital, Linkoeping
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy subjects
Exclusion criteria
* significant disease and disabilities that hinder running
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| markers for cardiovascular disease | 3 months | Insulin levels, glucose levels, lipids, hs-CRP, troponin T |
Countries
Sweden
Outcome results
None listed