Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01273935

Enrollment

400

Registered

2011-01-11

Start date

2010-01-31

Completion date

2010-12-31

Last updated

2011-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Test the Efficacy of Antiplatelet Regimes in Acute Stroke

Keywords

Aspirin, Acute Cerebrovascular Ischemia, Platelet Function

Brief summary

The aim of this study is to evaluate the low-response prevalence of early antiplatelet therapy and to test the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).

Detailed description

Antiplatelet agents are important therapeutic options in treating patients with acute ischemic strokes to prevent recurrent ischemic events or death. The aim of this study was to evaluate the low-response prevalence of early antiplatelet therapy and the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* suspected acute cerebrovascular ischemic events and patients who were admitted to the stroke unit where antiplatelet therapy was initiated

Exclusion criteria

* severe liver disorders, current gastrointestinal disorders, congestive heart failure, life-threatening malignancies and a personal or family history of bleeding disorders

Design outcomes

Primary

Measure	Time frame	Description
Result of platelet function test	—	Aggregometry result of antiplatelet therapy

Countries

Germany

Outcome results