Diabetes, Metabolic Syndrome
Conditions
Brief summary
The metabolic syndrome is a collection of related risk factors that predispose to the development of type 2 diabetes Mellitus and cardiovascular disease. The investigators will examine the hypothesis that the metabolic and genomic characteristics of patients with metabolic syndrome and/or diabetes that are at risk for developing complications differ from each other and can be detected using specific biomarkers in blood or in the exhaled breath. Early detection of these individuals will enable personalized treatment to prevent and treat diabetes and its complications
Detailed description
Breath samples will be collected in inert respiratory bag from diabetic and healthy volunteers, and analyzed using a chamber containing nano-chemical sensors. These samples together with blood samples will additionally be characterized using Gas Chromatography-Mass Spectroscopy GC-MS.
Interventions
OTHERBreath analysis and blood analysis
Exhaled breath and blood samples will be collected and further tested using Gas Chromatography-Mass Spectroscopy system.
Sponsors
Technion, Israel Institute of Technology
Rambam Health Care Campus
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Metabolic Syndrome * Type 2 diabetes * Healthy volunteers with 20\<Body Mass Index\<25
Exclusion criteria
* Smoking * Chronic or acute lung disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development of Diabetes or complication | 2 years |
Countries
Israel
Contacts
Primary ContactEddy Karnieli, MD
Backup ContactMargalit Levy, BA
Outcome results
None listed