Adenotonsillar Hypertrophy,Under 12 Years.
Conditions
Keywords
Adenotonsillectomy.
Brief summary
Null hypothesis; The efficacy of Enhancin\]Co-Amoxiclav given as a single intravenous dose at induction is not better than a five days oral course of the same given postoperatively in reducing postoperative morbidity after adenotonsillectomy.
Detailed description
Adenotonsillectomy results in morbidity that is reduced by the use of antibiotics.This study had the sole objective of comparing two route of administration to see which has superior results.
Interventions
DRUGEnhancin
Intravenous Enhancin at induction at a dose of 25 mg/kg amoxycillin equivalent. Oral dose of the same at the same dosage for the active comparator arm.
Sponsors
University of Nairobi
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
No minimum to 12 Years
Healthy volunteers
No
Inclusion criteria
* Patients below 12year scheduled to undergo adenotonsillectomy whose parents or guardians give consent for recruitment into the study.
Exclusion criteria
* Non consenting parents or guardians. Antibiotic use in the week preceding surgery. Patients with co mordities. Known allergies to Co-amoxiclav. Patients who develop complication that warrant change of antibiotic.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| POSTOPERATIVE FEVER | OPERATION DAY TO 7 DAYS POSTOPERATIVELY | Temperature monitored at 1st ,4th and 7th postoperative days. |
Countries
Kenya
Outcome results
None listed