Delirium, Dementia
Conditions
Keywords
Delirium, Dementia, Non-pharmacological Intervention, Post-acute care
Brief summary
The purpose of this study is to test the effectiveness of cognitively stimulating activities for resolving delirium in people with dementia.
Detailed description
The primary aim in this RCT is to test the efficacy of Recreational Stimulation for Elders as a Vehicle to resolve DSD (RESERVE- DSD). The investigators will randomize 256 subjects, newly admitted to post acute care, to intervention (RESERVE-DSD) or control (usual care). Intervention subjects will receive 30-minute sessions of tailored cognitively stimulating recreational activities for up to 30 days. The investigators hypothesize that subjects who receive RESERVE-DSD will have: decreased severity and duration of delirium; greater gains in attention, orientation, memory, abstract thinking, and executive functioning; and greater gains in physical function compared to subjects with DSD who receive usual care. The investigators will also evaluate potential moderators of intervention efficacy (lifetime of complex mental activities and APOE status). The secondary aim is to describe the costs associated with RESERVE-DSD.
Interventions
BEHAVIORALCognitive Stimulation
Thirty minutes of cognitive stimulation delivered daily for thirty minutes.
Sponsors
Penn State University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* presence of delirium * mild to moderate cognitive impairments * 65 years of age or older * English speaking * community-dwelling * legally authorized representative available
Exclusion criteria
* severe vision or hearing problems * diagnosis of 1. major depression 2. Parkinson's with Lewy Body disease 3. Huntington's disease 4. normal pressure hydrocephalus 5. seizure disorder 6. subdural hematoma 7. head trauma 8. known structural brain abnormalities 9. acute CVA/stroke 10. acute psychiatric condition * life expectancy \< 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Confusion Assessment Method | Averaged over 30 days or until discharge, whichever comes first |
| Delirium Rating Scale | Averaged over 30 days or until discharge, whichever comes first |
Secondary
| Measure | Time frame |
|---|---|
| Abstract Thinking | Averaged over 30 days or until discharge, whichever comes first |
| Orientation | Averaged over 30 days or until discharge, whichever comes first |
| Attention | Averaged over 30 days or until discharge, whichever comes first |
| Physical Function | Averaged over 30 days or until discharge, whichever comes first |
| Executive Function | Averaged over 30 days or until discharge, whichever comes first |
| Memory | Averaged over 30 days or until discharge, whichever comes first |
Countries
United States
Outcome results
None listed