Colon Cancer, Endometrial Cancer
Conditions
Keywords
To asses the biological actions of insulin analogs in primary tumor cells
Brief summary
Recently the general medical literature has become aware that the use of certain long-acting insulin analogues could potentially increase cancer risk.During the last few years the investigators group generated information of both scientific and clinical relevance on the proliferative and anti-apoptotic actions of insulin analogues. The goal of this project is to evaluate the hypothesis that the proliferative and signalling activities elicited by insulin analogues may have a impact on tumor behavior. In this study the investigators will asses the biological actions of insulin analogs in primary tumor cells of endometrial and colon cancer.
Interventions
OTHERTissue sample from tumor
Endometrial cancer specimens will be obtained from patients operated and treated at the Gynecologic Oncology Unit at Meir Medical Center. Colon cancer specimens will be obtained from patients that underwent colonoscopy at the Gastrointestinal Department at Meir Medical Center.
Sponsors
Tel Aviv University
Meir Medical Center
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 90 Years
Inclusion criteria
* Patients with Endometrial and Colon Cancer
Exclusion criteria
* None
Contacts
Primary ContactIlan Bruchim, MD
Outcome results
None listed