Cerebral Oxygenation, Intracranial Haemorrhagia
Conditions
Keywords
preterm infant,cerebral oxygenation, intracranial haemorrhagia
Brief summary
The aim of the study was investigated the cerebral tissue oxygenation index (c-TOI) measured by near infrared spectroscopy (NIRS)in the preterm infants with intracranial haemorrhagia.
Interventions
Continuous wave NIRS is a method for measurement of cerebral oxygenation and haemodynamics. This method is non-invasive, continuous, and can also be used as bedside monitoring. With continuous wave NIRS only changes in concentration of oxyhaemoglobin (O2Hb) and deoxyhaemoglobin (HHb) can be measured, not the absolute level of these parameters. It has been shown that changes in concentration of HbD (O2Hb - HHb) reflect changes in CBF. So, continuous monitoring of changes in concentration of HbD can be used as an indicator of changes in CBF, but changes in CBV will also influence the HbD signal, as will changes in arterial O2 saturation (saO2) and changes in cerebral metabolic rate for oxygen.
Sponsors
Study design
Eligibility
Inclusion criteria
.\<34 gestation week preterm infants with intracranial haemorrhagia
Exclusion criteria
* sepsis * NEC * congenital abnormalities * hydrocephalus * intracranial infections
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cerebral oxygenation | 6 months |
Countries
Turkey (Türkiye)