Sperm Selection
Conditions
Brief summary
In spite of the achievements and developement of the assisted reproduction techniques in the last years, there is still an elevated percentage of unsuccessful treatments, needing sometimes repeated attempts to reach pregnancy. The molecular physiology of sperm is being better characterized, and some reports have demonstrated the implication of different molecular processes in the pathophysiology of male infertility. Recently, different sperm selection methods have been based on these molecular differences, showing a better quality of the sperm population after selection. The main objective of this research project is to clinically apply these techniques in order to increase the pregnancy rates per cycle in infertile couples attending assisted reproduction treatments.
Interventions
OTHERNegative selection
Sperm selection to continue the treatment with healthy sperm
Sponsors
Instituto Valenciano de Infertilidad, IVI VALENCIA
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 37 Years
Healthy volunteers
Yes
Inclusion criteria
MEN: \- \>3million sperm after swimming process WOMEN: * \< 37 YEARS OLD * NO GYNECOLOGICAL ANOMOLIES * HORMONAL VALUES WITHIN CLINICAL RANGE
Exclusion criteria
* NONE
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gestation | 14 days | Sperm selection and blood sample confirming gestation |
Countries
Spain
Outcome results
None listed