Acute Stroke
Conditions
Keywords
oral health, oral hygiene, bacteria, quality of life, Clinical oral health in patients following acute stroke, Oral opportunistic pathogens in patients following acute stroke, Oral health-related quality of life in patients following acute stroke
Brief summary
The main aim of this oral health intervention project is to compare the effect of providing 1) professional oral hygiene instruction alone versus 2) professional oral hygiene instruction plus adjunctive Chlorhexidine mouth rinse versus 3) professional oral hygiene instruction plus adjunctive assisted tooth brushing and Chlorhexidine mouth rinse, on the oral health condition, the general health condition and health-related quality of life (HRQoL) of patients with stroke who are receiving hospital-based rehabilitation. An additional aim is to assess potential longer term oral intervention-related health and HRQoL outcomes.
Interventions
Oral health promotion intervention
Sponsors
The University of Hong Kong
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Aged 50 years and over * Moderate to severe stroke (Barthel Index \>/= 70) * Admitted to Rehabilitation Unit within 7 days
Exclusion criteria
* Patients with naso-gastric feeding tube * Edentulous patients * Patients with communication difficulties
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in plaque scores over course of trial | Three week in-hospital rehabilitation period |
Secondary
| Measure | Time frame |
|---|---|
| Change in oral colonization by aerobic and facultatively anaerobic Gram-negative bacilli over course of trial | Three week in-hospital rehabilitation period |
| Change in oral colonization by Staphylococcus aureus over course of trial | Three week in-hospital rehabilitation period |
| Change in gingival bleeding scores over course of trial | three week in-hospital rehabilitation period |
| Change in health-related quality of life over course of trial | three week in-hospital rehabilitation period |
| Change in oral health-related quality of life over course of trial | Three week in-hospital rehabilitation period |
| Change in oral colonization by yeasts over course of trial | Three week in-hospital rehabilitation period |
Countries
Hong Kong
Outcome results
None listed