Antibiotic Prophylaxis in Mesh Repair of Inguinal Hernias

Single Dose Antibiotic Prophylaxis in Lihtenstein Repair for Primary Inguinal Hernias

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01264003

Enrollment

200

Registered

2010-12-21

Start date

2008-05-31

Completion date

2010-12-31

Last updated

2010-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inguinal Hernia

Keywords

inguinal hernia, antibiotic, prophylaxis

Brief summary

Inguinal hernia repairs is clean surgical procedures. However infection may be a concern when prosthetic materials are used. This prospective randomized study has been set to observe if antibiotic prohylaxis is of benefit in mesh repair of inguinal hernias.

Detailed description

There are two group in the study. Control group received no antibiotic prohylaxis, whereas a single dose 1 gr. intravenous cefazoline is given to the patient in prophylaxis arm of the study. 30-days surgical site infection rates and 1 year prosthetic intervention late infection rates are observed and recorded. Side effects of antibiotic used are also recorded.

Interventions

DRUGsefazolin

In prophylaxis

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

inguinal hernia repair -

Exclusion criteria

uncontrolled diabetes mellitus, \-

Design outcomes

Primary

Measure	Time frame
Surgical site infection	30 days postoperatively

Secondary

Measure	Time frame
Drug side effects	5 days postoperatively
1-year prosthetic repair surgical site late infection rate	1 year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026