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Optimization of Preventive Effects of Physical Training

Optimization of Preventive Effects of Physical Training Saarländische Ausdauer-Etappe (SAusE)

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01263522
Acronym
SAusE
Enrollment
266
Registered
2010-12-20
Start date
2010-12-31
Completion date
2013-12-31
Last updated
2018-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Prevention, Cardiovascular Risk Factor Management, Size of Response to Training

Keywords

primary prevention, endurance, cardiovascular risk factors, training, exercise, non-responder

Brief summary

Health-promoting effects of physical exercise are well-investigated especially for endurance activities. However, for different individuals, positive effects have different sizes, even non-responders are observed. Other forms of training, such as strength training and interval training, are less well investigated. Therefore, a comparative longitudinal training study is warranted to examine differences of preventive effects (outcome measures: ergometric descriptors of physical performance, established risk factors and prognostic factors for cardiovascular diseases) of continuous endurance training, interval training and strength endurance training. In a second stage, the observed non-responders will perform a different type of training (cross-over). It is expected, that besides a comparative general efficacy evaluation of the three training types, improved recommendations for optimized individualization of training parameters can be formulated.

Interventions

OTHERdifferent training programs

two different endurance programs and one strength endurance program

OTHERcontrol condition

unchanged lifestyle

Sponsors

Universität des Saarlandes
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
30 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* untrained * healthy * non-smoking

Exclusion criteria

* Contraindications for physical activity * BMI \> 30 kg/m2 * resting blood pressure \> 160/100 mmHg * diabetes * total cholesterol \> 300 mg/dl * maximal oxygen uptake \> 50 ml/min/kg for men and \> 45 ml/min/kg for women respectively * other complaints or diseases that might interfere with exercise training

Design outcomes

Primary

MeasureTime frameDescription
VO2 max6 monthsdetermined during treadmill testing

Secondary

MeasureTime frameDescription
resting heart rate6 months
resting blood pressure6 months
blood lipid profile6 monthsratio: total cholesterol/HDL-cholesterol

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026