Primary Prevention, Cardiovascular Risk Factor Management, Size of Response to Training
Conditions
Keywords
primary prevention, endurance, cardiovascular risk factors, training, exercise, non-responder
Brief summary
Health-promoting effects of physical exercise are well-investigated especially for endurance activities. However, for different individuals, positive effects have different sizes, even non-responders are observed. Other forms of training, such as strength training and interval training, are less well investigated. Therefore, a comparative longitudinal training study is warranted to examine differences of preventive effects (outcome measures: ergometric descriptors of physical performance, established risk factors and prognostic factors for cardiovascular diseases) of continuous endurance training, interval training and strength endurance training. In a second stage, the observed non-responders will perform a different type of training (cross-over). It is expected, that besides a comparative general efficacy evaluation of the three training types, improved recommendations for optimized individualization of training parameters can be formulated.
Interventions
two different endurance programs and one strength endurance program
unchanged lifestyle
Sponsors
Study design
Eligibility
Inclusion criteria
* untrained * healthy * non-smoking
Exclusion criteria
* Contraindications for physical activity * BMI \> 30 kg/m2 * resting blood pressure \> 160/100 mmHg * diabetes * total cholesterol \> 300 mg/dl * maximal oxygen uptake \> 50 ml/min/kg for men and \> 45 ml/min/kg for women respectively * other complaints or diseases that might interfere with exercise training
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VO2 max | 6 months | determined during treadmill testing |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| resting heart rate | 6 months | — |
| resting blood pressure | 6 months | — |
| blood lipid profile | 6 months | ratio: total cholesterol/HDL-cholesterol |
Countries
Germany