Endometrial Cancer, Esophageal Carcinoma, Fallopian Tube Cancer, Gastrointestinal Carcinoma, Lung Cancer, Ovarian Cancer, Pancreatic Carcinoma, Peritoneal Cancer
Conditions
Keywords
NBI, ENDOMETRIUM, FALLOPIAN TUBE, OVARY, PERITONEUM, Surgery, Lung, Pancreatic, Esophageal, thorascopic, laparoscopic, robotic, 10-180
Brief summary
The purpose of this study is to determine whether narrowband imaging (NBI) makes it easier for a surgeon to see cancer. NBI is a kind of light. Normally, white light is used during surgery. White light uses many wavelengths of light. NBI only uses two wavelengths which highlight the blood vessels. This makes it easier for the surgeon to see blood vessels. Tumors often have more blood vessels than normal tissue. As a result, NBI may make it easier for the surgeon to see small tumors. In this study the surgeon will look with both normal white light and NBI. This way a comparison can be made to determine which is superior. Improved identification of tumors allows doctors and patients to make informed decisions about whether treatment is needed after surgery. It also provides additional information to determine which treatments may be best.
Interventions
The intervention is visual assessment of the peritoneal or pleural surface with NBI followed by biopsy and photographic documentation of any abnormal lesions. Photograph or video of abnormality(ies) under white light and NBI.
Sponsors
Memorial Sloan Kettering Cancer Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients must meet one (or more) of the following criteria: * Preoperative diagnosis of ovarian, fallopian tube, or primary peritoneal carcinoma (all stage, grade and histology) * Preoperative diagnosis of grade III endometrial carcinoma (all stage, all histology) * Preoperative diagnosis of uterine serous carcinoma (all stage, all grade) * Preoperative diagnosis of clear cell endometrial carcinoma (all stage, all grade) * Preoperative diagnosis of endometrial carcinosarcoma (all stage, all grade) * Gastrointestinal carcinoma (all histology, stage and grade) * Pancreatic carcinoma (all histology, stage and grade) * Lung cancer (all histology, stage and grade) * Esophageal carcinoma (all histology, stage and grade) * Suspected or pathologically confirmed metastatic disease to the lung (all disease primaries) * Suspected or pathologically confirmed malignant pleural effusion (all disease primaries) Patients must meet all of the following criteria: * Planned thorascopic robotic or laparoscopic surgical approach * \>18 years old * Not pregnant * Able to give consent Participation in other research protocols does not exclude a patient from participation in this study.
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine the feasibility of Narrow Band Imaging (NBI) at the time of thorascopic, laparoscopic or robotic surgery. | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Determine what percentage of patients have surface metastasis identified with NBI that were not seen on white light imaging. | 1 year |
Countries
United States
Outcome results
None listed