Chronic Pain
Conditions
Keywords
Chronic pain, Electric Stimulation Therapy, Neurologic Examination
Brief summary
The primary purpose is to study the effect of spinal cord stimulation (SCS) on sensory parameters, using quantitative sensory testing (QST). Patients with established SCS treatment will be examined with QST. Subjects will be randomized to have their SCS device turned off or kept active (1:1) for a 12-hour period, then be reexamined using the same QST protocol. After the 2nd examination all patients cross over (ie. inactive devices are activated, active devices are deactivated) and are reexamined after a new 12-hour period. The investigators expect to demonstrate that SCS treatment has a significant effect on sensory parameters associated with pain hypersensitivity but no significant effect on sensory parameters associated with detection of non-painful stimuli.
Interventions
DEVICEActive SCS
SCS IPG activated
DEVICEDeactivated
SCS IPG deactivated
Sponsors
Danish Pain Research Center
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* minimum age 18 * able to understand participant information and cooperate at the neurological examination * uncomplicated treatment with spinal cord stimulation for at least 3 months * pain in only one extremity * treatment effect in only one extremity
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in sensory parameters | 24 hours |
Countries
Denmark
Outcome results
None listed