Cocaine Addiction, Transcranial Magnetic Stimilation, Treatment
Conditions
Brief summary
Cocaine addiction is a serious disease. Nowadays we still have no efficient method reducing craving and extending the abstinence period of this patients during treatment. The aim of this study is to evaluate reduction if craving and other parameters related to addiction within this group of patients through a treatment with transcranial magnetic stimulation.
Detailed description
Patients are going to submitted do a course of rTMS of one month, each session up to 15 minutes. After the rTMS they are going to be offered cognitive therapy to prevent relapse. The area stimulated is the dorso-lateral prefrontal cortex. This technique was employed in previous studies and the risks are insignificant.
Interventions
PROCEDURETranscranial Magnetic Stimulation
5 Hz, 120 % motor threshold, intertrain interval 20s, number of pulses in train 50.
Sponsors
University of Sao Paulo General Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Minimum age of 18 * Maximum age of 40 * Diagnostic of Cocaine addiction * Willingly participate the study
Exclusion criteria
* Metallic Cerebral Implant * History of Severe Brain trauma or injury * Organic Brain Disease * Severe Somatic Disease * History of other actual or past psychiatric diagnostics
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Minnesota Cocaine Craving Scale(MCCS) | 2 months | Reduction on the scores of MCCS |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Barrat Impulsiveness Scale vers 11 ( BIS 11) | 2 months | Reduction of scores of BIS 11. |
Countries
Brazil
Contacts
Primary ContactPhilip L Ribeiro, MD
Outcome results
None listed