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Research in Autism: Parent Intervention

Research in Autism: Parent Intervention

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01258465
Enrollment
39
Registered
2010-12-13
Start date
2005-01-31
Completion date
2009-12-31
Last updated
2010-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autistic Disorder

Keywords

Communication, Pivotal Response Training, Picture Exchange Communication System

Brief summary

The purpose of this research project was to systematically compare two widely used types of intervention programs for children with autism within a parent training model. In one condition, randomly assigned children were provided with an intervention that typically results in acquisition of expressive words in a large percentage of children diagnosed as having autism, using a well-documented manualized intervention focused on verbal expressive communication only (Pivotal Response Training, PRT). In the other condi¬tion, randomly assigned children received a widely used intervention on the same social communication functions using a well-documented manualized augmentative system of intervention (Picture Exchange Communica¬tion System, PECS) that has been reported to produce verbal and nonverbal communication in large percentages of children diagnosed with autism. Children in the two conditions were compared for development of verbal and nonverbal communication, changes in disruptive behavior, changes in symptoms of autism, and general adaptive behavior gains. In addition, parent satisfaction and stress measures were gathered in order to assess the effects of each intervention on family functioning.

Interventions

Naturalistic behavioral protocol designed to teach vocal communication.

BEHAVIORALPicture Exchange Communication System

Pictorially-based behavioral protocol designed to teach communication to nonverbal children via pictures icons.

Sponsors

University of California, San Diego
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
24 Months to 47 Months
Healthy volunteers
No

Inclusion criteria

* Diagnosis of Autistic Disorder or At Risk of Autistic Disorder * Age 2-0 to 3-11 years of age * Use of fewer than 10 functional words at intake

Exclusion criteria

* Primary diagnosis of mental retardation * Neurologic pathology (e.g., PKU, encephalitis, brain trauma) * Major sensory impairment

Design outcomes

Primary

MeasureTime frame
Mullen Scales of Early Learning23 weeks with three months follow-up

Secondary

MeasureTime frame
Vineland Adaptive Behavior Scales23 weeks and 3 month follow up

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026