Patients Undergoing Major Abdominal Surgery
Conditions
Brief summary
The purpose of this study is to analyze the peri-operative expression of pancreatic stone protein and pancreatitis-associated protein in surgical patients following major abdominal surgery by blood samples.
Interventions
OTHERAnalysis of PSP and PAP from venous blood samples
to analyse the peri-operative expression of pancreatic stone protein in surgical patients following major abdominal surgery
Sponsors
University of Zurich
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
- \>= 18 years * abdominal major surgery * need for post-operative ICU care
Exclusion criteria
- \<18 years \- patients who do not agree the written informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosed Infections according to the Systemic Inflammatory Response System (SIRS) Criteria of the german interdisciplinary Association of Intensive and Emergency Medicine | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Intensive Care Unit (ICU) stay in days | 2 years |
| hospital stay in days | 2 years |
| postoperative complications according to the Clavien-Dindo Classification System | 2 years |
| hospital costs | 2 years |
| comparisons to other known infectious parameters: c-reactive protein (CRP), procalcitonin (PCT), Interleukin 6 (IL-6), Tumor Necrosis Factor Alpha (TNF-alpha), Leucocytes | 2 years |
| Bacteriaemia in the blood | 2 years |
| Platelets in the blood | 2 years |
Countries
Switzerland
Outcome results
None listed