Allogene MSCs Transplantation, Chronic Liver Diseases Patients, Peripheral Vein
Conditions
Keywords
allogene MSCs, transplantation, chronic liver diseases, peripheral vein
Brief summary
Allogene MSCs transplantation will be performed in patients with chronic liver diseases through peripheral vein and therapeutic effects including short-term effects and long-term follow-up will be compared and investigated.
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
1. chronic liver diseases including: viral hepatitis, alcoholic liver disease, autoimmune liver disease. 2. age: 15-65 years old.
Exclusion criteria
1. pregnant women and women in lactation. 2. other systems and organs disfunction 3. space-occupying lesion were found in liver. 4. concurrent infection with HIV and other immunodeficiency diseases. 5. DIC and active bleeding were confirmed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short-term therapeutic effects at 1-8 weeks after Allogene MSCs transplantation through peripheral vein. | 1-8 weeks after transplantation |
Secondary
| Measure | Time frame |
|---|---|
| Long-term follow-up of Allogene MSCs transplantation through peripheral vein. | 3-60 months |
Countries
China