Impact of IPT With Sulfadoxin Pyrimetamin on Pregnant Women and Their Babies Outcomes in Peri-urban Areas of Bobo-Dioulasso(Burkina Faso)

Impact of Intermittent Preventive Treatment (IPT) With Sulfadoxine-pyrimethamine (SP) on the Morbidities Associated With Malaria in Pregnant Women and Newborns in Peri-urban Areas of Bobo-Dioulasso, 5 Years After Its Adoption by the National Program for Fight Against Malaria in Burkina Faso.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01255605

Enrollment

772

Registered

2010-12-07

Start date

2010-09-30

Completion date

2011-06-30

Last updated

2012-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria, Pregnancy

Keywords

Intermittent preventive treatment with sulfadoxin-pyrimethamine, in Bobo-Dioulasso peri-urban areas, 5 years after its implementation, Burkina Faso.

Brief summary

The purpose of this is to determine the impact of intermittent preventive treatment (IPT) with sulfadoxine-pyrimethamine (SP) on the morbidities associated with malaria in pregnant women and newborns in rural peri-urban areas of Bobo-Dioulasso, 5 years after its implemented.

Detailed description

Malaria in pregnant women is a crucial issue in Burkina Faso. Faced with this problem, a strategy based on the use of treated nets and intermittent preventive treatment (IPT) based on sulfadoxine-pyrimethamine (SP) was adopted in 2005. Five years after its implementation, the investigators will check whether this strategy is still effective in the preventing maternal and congenital malaria on the one hand and maternal anemia, low birth weight and prematurity on the other hand.

Interventions

None listed

Study design

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Residing in the health area of Lafiabougou or secteur 24 * Having agreed to give free and informed consent

Exclusion criteria

* Bleeding from during the pregnancy * eclampsia

Design outcomes

Primary

Measure	Time frame	Description
Peripheral and placental malaria	Peripheral malaria : at antenatal clinics and at delivery. Placental malaria: at delivery	The investigators will check if pregnant women have any malaria parasites by making a finger prick thick respectively at antenatal clinics and at delivery. A placental thin smear will be made at delivery.

Secondary

Measure	Time frame	Description
Maternal anemia, congenital malaria,low birth weight, prematurity.	Maternal anemia: at antenatal clinics and at delivery. Congenital malaria: at delivery. Low birth weight: at delivery. Prematurity: at delivery.	The investigators will check pregnant women haemoglobin level.A level\< 11g/dl will be considered as anemia. Congenital malaria will be assessed through cord blood smear. Birth weight \<2500g will be considered as low birth weight. Prematurity designs any birth before 37 gestation weeks.

Countries

Burkina Faso

Outcome results