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Oxygen Peripheral Saturations and Lung Surgery

Evaluation of the Continuous Measurement of Tissular (StO2) and Cerebral (ScO2) Oxygenation During Lung Surgery and During the 6 First Postoperative Hours (Prospective Monocentric Study).

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01255033
Enrollment
47
Registered
2010-12-07
Start date
2010-11-30
Completion date
2011-06-30
Last updated
2016-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Surgical Procedures, Recovery Period

Keywords

perioperative surgery, regional oxygenation, hypoxemia, brain hypoxemia, spectroscopy, near-infrared

Brief summary

The purpose of this study is to compare the ability of two peripheral and non invasive devices to detect hypoxic events during one-lung ventilation and during the early postoperative period. One device measures regional cerebral oxygenation and the other muscular oxygenation. These two devices are compared to non invasive arterial saturation (SpO2), which is the gold standard.

Detailed description

Lung surgery is often complicated by hypoxic evants : * during one-lung ventilation which leads to changes about ratio in ventilated and perfused lung areas. This blood flow redistribution promotes shunt with a decreased arterial oxygenation and possible hypoxemia. * during the postoperative period. Common measure of arterial saturation through SpO2 may miss a great number of hypoxic events with regional impact because a significant decrease in SpO2 occurs for an arterial pressure in oxygen below 60 mmHg. Currently, cerebral and somatic saturation can be monitored non-invasively and continuously via optical sensors applied to the right and left forehead and to the thenar eminence. These devices may help clinicians in the detection of such hypoxemic events.

Interventions

DEVICEMonitoring of tissular oxygenation

Equanox: cerebral oxygenation by spectroscopy, near-infrared through forehead and noninvasive devices Inspectra: tissular oxygenation by spectroscopy, near-infrared through thenar and noninvasive device

Sponsors

Hopital Foch
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Scheduled lung surgery requiring one-lung ventilation * informed consent

Exclusion criteria

* Pregnant woman * Neurologic or psychiatric disorders

Design outcomes

Primary

MeasureTime frameDescription
Desaturation during surgery and early postoperative recovery whatever the device.6 hours postoperativeNumber of episodes

Secondary

MeasureTime frame
Chronology between devices in case of desaturation6 hours post operative
Quality of signal6 hours postoperative

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026