Glaucoma
Conditions
Brief summary
In this study the investigators are going to study the retinal nerve fibers layers (RNFL) modification of two groups of patients, one taking no drugs, the other taking forskolin, rutin and vitamins B1 and B2.
Interventions
DRUGforskolin, rutin and vitamins B1 and B2
Sponsors
vingolo enzo maria
domanico daniela
salvatore serena
University of Roma La Sapienza
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Inclusion criteria
* Age (30-80 years); * Baseline Intraocular pressure (IOP) (20-32 mmHg): average untreated Intra Ocular Pressure (IOP) for both eyes as determined from 2 to 4 visits within a 6-months period; * Central Corneal Thickness (CCT) (475-650 µm): average of 3 different measurements from both eyes during the same visit; * Pattern standard deviation (PSD) (0,50-3,00 dB) average of both eyes as stated on the most recent visual field index report * Vertical Cup/Disk ratio (0,00-0,80): average of both eyes * All these data were entered into a calculator specially designed for STAR (Scoring Tool for assessing risk) II parameter. The patients were divided into low-, moderate- and high risk groups according to the result given by the calculator.
Exclusion criteria
-other ocular pathologies than glaucoma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| retinal nerve fibres layer thickness | — |
Secondary
| Measure | Time frame |
|---|---|
| global risk threshold for glaucoma progression | — |
Countries
Italy
Outcome results
None listed