Dry Eye Syndrome
Conditions
Keywords
Dry Eye, Ocular Retention Time
Brief summary
The purpose of this study is to evaluate the ocular retention time of Systane Ultra compared to Hialid and saline.
Interventions
One drop in study eye, one time, during office visit.
OTHERHialid 0.1 Artificial Tears Eye Drops
One drop in study eye, one time, during office visit.
One drop in study eye, one time, during office visit.
Sponsors
Alcon Research
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosed with mild to moderate dry eye as defined in the protocol. * Able and willing to follow instructions. * Other protocol-defined inclusion criteria may apply.
Exclusion criteria
* Any medical condition that may affect the results of the study. * History or evidence of ocular or intraocular surgery within the past six months. * History of intolerance or hypersensitivity to any component of the study medications. * Use of concomitant topical ocular medications during the study period. * Ocular conditions that may preclude safe administration of the test article. * Unwilling to discontinue contact lens wear during the study period. * Participation in an investigational drug or device study within 30 days of enrollment. * Other protocol-defined
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ocular surface residence time | Time to event | Ocular surface residence time is defined as the time for fluorescence intensity to return to baseline value after a drop of ophthalmic dye is instilled in the study eye. Dye retention will be measured with a fluorophotometer. |
Outcome results
None listed