Retrospective Review of CT and MR in Pediatric Patients With Cholestasis

Retrospective Review of Computed Tomography and Magnetic Resonance Images in Pediatric Patients With Cholestasis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01252043

Enrollment

Registered

2010-12-02

Start date

2010-10-31

Completion date

2011-10-31

Last updated

2010-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children, Cholestasis

Keywords

cholestasis, children

Brief summary

The investigators will try to predict the risk of esophageal varices (EVs) in long-term BA survivors using noninvasive computed tomography (CT) or magnetic resonance (MR) indices and the measurement of transverse diameters of paraesophageal and gastroesophageal veins.

Detailed description

We intend to review retrospectively 80 pediatric patients on an average of 2 years, who underwent 64-slice CT or MR examinations between January 2005 and Oct 2010 and had EVs on esophagogastroduodenoscopy. Splenic diameters (mm) and hepatic diameters of all patients were measured. Splenic and hepatic volume indices also calculated. The transverse diameters of paraesophageal varices (PVs) and perigastric varices (PGVs) were measured adjacent to the lower thoracic esophagus and within the lesser sac, respectively. We will try to find out the possible splenic, hepatic or vascular predicting factors useful to evaluate the risk of clinically evident esophageal varices.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 18 Years

Healthy volunteers

Inclusion criteria

* all cholestatic children with CT, MR and complete medical record

Exclusion criteria

* all cholestatic children without either CT, MR or complete medical record

Design outcomes

Primary

Measure	Time frame
esophageal variceal bleeding	retrospective review

Countries

Taiwan

Contacts

Primary ContactSteven SF Peng, M.D.

sfpeng@ntuh.gov.tw886-2-23123456

Outcome results