Endothelial Dysfunction, Erectile Dysfunction
Conditions
Brief summary
1. Find the early diagnostic markers of erectile dysfunction; 2. Study the warning role of ED in some diseases.
Interventions
None listed
Sponsors
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sun Yat-sen University
Study design
Observational model
CASE_CONTROL
Eligibility
Sex/Gender
MALE
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
1. Male and at least 18 years of age. 2. Provide signed informed consent. 3. Have a history of erectile dysfunction (ED: defined as a consistent change in the quality of erection that adversely affects the subject's satisfaction with sexual intercourse) . 4. Have a stable monogamous relationship with a female partner. To some subjects with poor sexual experience, re-evaluation would be conducted after a 4-weeks sex education. 5. Make at least four sexual intercourse attempts with the female sexual study partner during the 4-week therapeutic period without medication. 6. Agree not to use any other ED treatment for at least 4 weeks.
Exclusion criteria
1. severe diseases (such as congestive heart failure, arrhythmia, significant renal or hepatic dysfunction and anemia); 2. Had clinically noteworthy penile deformities, pelvic surgery or trauma of perineal region; 3. Had received long-term pharmacotherapy (including antioxidant agents, vitamins and traditional Chinese drugs). 4. An addiction problem (with a history of injection or administration of opium, poppy, heroin, hemp, morphine, cocaine, caffeine, ketamine and meperidine etc.)
Countries
China
Contacts
Primary ContactChunhua Deng, MD, PhD
Backup ContactYanping Huang, MD
Outcome results
None listed