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Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail

Volatile Anesthetic Protection Of Renal Transplants: VAPOR-1-trail

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01248871
Enrollment
120
Registered
2010-11-25
Start date
2010-09-30
Completion date
2012-10-31
Last updated
2024-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Donation/Transplantation

Keywords

renal, transplantation, Volatile, anesthetic

Brief summary

To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients undergoing living donor kidney donation/transplantation.

Interventions

DRUGprocedure:sevoflurane-remifentanil/sufentanil

Active Comparator

DRUGvolatile agent only during reperfusion

Active Comparator

DRUGpropofol-remifentanil/sufentanil

Active Comparator

Sponsors

University Medical Center Groningen
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* All patients: Age \> 18 years

Exclusion criteria

* patient refusal * BMI\< 17, \>35 * neurological disorder * recent use of psycho-active medication, including alcohol. * Donor-recipient couples from the ABO-incompatible program * Altruistic donor

Design outcomes

Primary

MeasureTime frame
To compare the renal protective properties of two currently used anaesthetic techniquesparticipants will be followed for the duration of hospital stay

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 10, 2026