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The Effect of Selective Laser Trabeculoplasty (SLT) on Ocular Rigidity

The Effect of Selective Laser Trabeculoplasty (SLT) on Ocular Rigidity

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01247831
Acronym
SLT/ORA
Enrollment
150
Registered
2010-11-24
Start date
2010-11-30
Completion date
2011-08-31
Last updated
2017-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Keywords

glaucoma, selective laser trabeculoplasty, ocular rigidity

Brief summary

The purpose of this study is to examine the influence of selective laser trabeculoplasty (SLT) on ocular rigidity in glaucoma patients.

Detailed description

Ocular Rigidity (corneal hysteresis and corneal resistance factor) is measured with the Ocular Response Analyzer (Reichert) before and 4 weeks after SLT (Q-switched 532 nm frequency doubled neodymium yttrium aluminium garnet laser with a spot size of 400 µm and a 3-ns pulse duration). The trabecular meshwork is treated with 100 spots over 360° and an energy of 0,8 mJ. The purpose is to examine if selective laser trabeculoplasty changes ocular rigidity.

Interventions

PROCEDURESelective Laser Trabeculoplasty

100 spots with an energy of 0,8 mJ are applied over 360° of the trabecular meshwork of glaucoma patients with a Q-switched 532 nm frequency doubled neodymium YAG Laser.

Sponsors

Technische Universität Dresden
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

glaucoma patients (primary open angle glaucoma, ocular hypertension) over the age of 18 who need further IOP reduction to control their glaucoma

Exclusion criteria

other forms of glaucoma (angle closure, secondary glaucoma, congenital, juvenile), acute psychosis, epilepsy

Design outcomes

Primary

MeasureTime frameDescription
change in ocular rigidity4 weeksIs there a change in ocular rigidity (corneal hysteresis, corneal resistance factor) as measured with the Ocular Response Analyzer (Reichert) after selective laser trabeculoplasty?

Secondary

MeasureTime frameDescription
IOP reduction4 weeksIs there an effective IOP drop after SLT?

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026