Comparison of Two Different Heart-lung Machine Filling Methods: Precoating Versus Colloidal Fluids

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01247051

Enrollment

Registered

2010-11-24

Start date

2011-01-31

Completion date

2011-08-31

Last updated

2011-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgery, Cardio Pulmonary Bypass, Priming

Keywords

priming, cardiac surgery, cardio pulmonary bypass, precoating

Brief summary

The study is a single-center, randomized, un-blinded treatment study in which patients (\>78 years) with the use off a heart-lung machine were provided into two study arms. Patient wit precoating have a filling of the machine with their own blood. In the comparator arm, a standard priming is used.

Interventions

PROCEDUREPrecoating

preoperative filling of heart lung machine with patients blood

PROCEDUREStandard priming

preoperative filling of heart lung machine with colloids

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

78 Years to 95 Years

Healthy volunteers

Inclusion criteria

* Age \> 78 years * CPB

Exclusion criteria

* Hb \<12 mg/dl * Off pump surgery

Design outcomes

Primary

Measure	Time frame
blood loss	24 hours

Secondary

Measure	Time frame
Inflammatory response	one week

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026