Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine

Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine?

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01245868

Enrollment

Registered

2010-11-23

Start date

2009-11-30

Completion date

2010-12-31

Last updated

2015-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Anesthesia

Keywords

Spinal anaesthesia, Bupivacaine, Lidocaine, Duration of blockade

Brief summary

The purpose of the study is to investigate if a small amount of lignocaine added to bupivacaine for spinal anesthesia to patients planned for arthroscopic knee surgery, can shorten the duration of the sensoric and the motoric blockade.

Interventions

DRUGLidocaine

DRUGbupivacaine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* The patient want spinal anaesthesia * No contradictions against spinal anaesthesia * Healthy people (ASA-score 1 or 2) * Body mass index \< 35 and between 155 and 190 cm

Exclusion criteria

* Known allergic reactions to planned drugs * Neurologic disturbances * Diabetes

Design outcomes

Primary

Measure	Time frame
Duration of spinal blockade	Repeating monitoring every 15 minutes after applying the blockade, up to 360 minutes.

Secondary

Measure	Time frame
Time to fulfillment of discharge criteria from the hospital.	Evaluated every 15 minutes after the operation up to 360 minutes. On average 200 to 300 minutes.

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026