The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01244360

Acronym

MUresv

Enrollment

Registered

2010-11-19

Start date

2010-11-30

Completion date

2011-06-30

Last updated

2011-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammation

Keywords

resveratrol, insulin, inflammation, cognition, metabolism

Brief summary

The purpose of this study is to examine the effects of resveratrol on health and human performance. The study will evaluate cognitive function and several indicators of physical health before and after taking a resveratrol supplement or a placebo for three weeks.

Detailed description

Measurements * blood laboratory parameters * cognitive assessment changes * body composition changes * vascular endothelial response

Interventions

DIETARY_SUPPLEMENTresveratrol

Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.

OTHERPlacebo Comparator: Sugar Pill

Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

45 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* men and women between 45 and 75 years of age * Normal heart rate and Blood pressure * Ability to use personal computer interface * Successful completion of physical activity readiness questionnaire

Exclusion criteria

* Cardiovascular disease, uncontrolled hypertension, lung disease * inability to tolerate exercise * have taken grape related supplement in past 12 months * current use of drugs or dietary supplements to enhance exercise performance * allergy to wine, grape juice or grape seed supplements

Design outcomes

Primary

Measure	Time frame	Description
Vascular function	4 weeks, with option of additional 4 week treatment period	vascular response to stress will be measured using flow mediated dilation and ultrasound.

Secondary

Measure	Time frame	Description
Body fat percentage	4 weeks, with optional additional 4 week treatment period	Body fat percentage will be measured using a DEXA scan.
inflammation biomarkers	4 weeks, with optional additional 4 week treatment period	Fasting blood draw
cognitive function	4 weeks, with optional additional 4 week treatment period	cognitive function will be assessed using a validated computer based assessment tool

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026