A Magnetic Resonance Imaging Study of Patients With Cervical Spondylosis

Structural Spinal Cord Integrity in Patients With Cervical Spondylosis in Relation to Clinical Status

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01243684

Acronym

Tractocervical

Enrollment

Registered

2010-11-18

Start date

2010-09-01

Completion date

2014-01-01

Last updated

2026-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Spondylosis

Keywords

Spinal cord, cervical spondylosis, myelopathy

Brief summary

This study aims at evaluating spinal cord structure using diffusion tensor imaging in patients with cervical spondylosis.

Detailed description

Diffusion tensor imaging (DTI) of the cervical spinal cord will be performed in patients with cervical spondylosis with varying degrees of symptoms and in healthy control subjects. Fibre tracking of main spinal tracts will be performed. Regions of interest will also be identified. Diffusion parameters will be extracted. This will allow quantification of degree of damage in of the spinal cord. The findings will be related to motor function measures and comprehensive clinical tests of sensory and motor function.

Interventions

DEVICEDTI - Diffusor Tensor Imaging

Radiology intervention

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* 18-70 years old * Sufficiently cooperative * Cognitively understands study and implications * Signed informed consent * Symptomatic cervical spondylosis

Exclusion criteria

* MRI contraindications (e.g., pacemaker, metal implants, claustrophobia) * Previous pathology that would impact behavioural measures * Anxiety and poor cooperation * Previous neurological condition * Pregnancy

Design outcomes

Primary

Measure	Time frame
DTI parameters in cervical spinal cord	3 weeks

Secondary

Measure	Time frame	Description
Clinical data, i.e., Muscle testing, sensory testing, reflexes, spasticity, and Motor function (dexterity test), grip strength	3 weeks	Clinical data, i.e., Muscle testing, sensory testing, reflexes, spasticity Motor function (dexterity test), grip strength

Countries

France

Contacts

PRINCIPAL_INVESTIGATORAntoine FEYDY, PhD

Assistance Publique Hopitaux de Paris

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026