Smoking
Conditions
Keywords
Smoking, surgery, Anesthesia, quit
Brief summary
The Objective of this study is to introduce a practically feasible multifaceted intervention in the preadmission clinic to help reduce smoking in preoperative surgical patients. The investigators aim to study the effectiveness of such a program in promoting positive change in smoking behavior among patients before surgery. The forced abstinence enforced on patients during hospital stay for their surgery can also be used to help smokers remain tobacco free long term. A significant percentage of surgical patients will be receptive to smoking cessation interventions in the preadmission clinic and will refrain from smoking at 24 and 52 weeks after starting the treatment.
Interventions
DRUGChampix
Days 1 - 3: 0.5 mg once daily (1 table each day) Days 4 - 7: 0.5 mg twice daily (1 in the morning and 1 in the evening) Days 8 - 12 weeks 1.0 mg twice daily (1 in the morning and 1 in the evening)
Sponsors
Pfizer
University Health Network, Toronto
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The investigators will recruit patients who are assessed in preadmission clinic and scheduled for elective surgical procedures within the next 8 to 30 days. * Patients should be 18 yrs of age, have smoked an average 10 cigarettes/day or more during the previous year and had no period of smoking abstinence longer than 3 months in the past year.
Exclusion criteria
* current pregnancy, breastfeeding; * major depression, panic disorder, psychosis, or bipolar disorder within the prior year; * use of nicotine replacement or bupropion within the previous 3 months; * cardiovascular disease within the past 6 months; * a serious or unstable disease within the past 6 months; * drug or alcohol abuse or dependence within the past year; * and use of tobacco products other than cigarettes or marijuana use within the previous month; * participating in any other studies * Patients who cannot understand English or have any form of cognitive impairment will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A significant percentage of surgical patients will be receptive to smoking cessation interventions in the preadmission clinic and will refrain from smoking at 24 and 52 weeks after starting the treatment. | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Patients who receive interventions but do not quit smoking will have reduced number of cigarettes consumed /day or improved stage of change (determined by Prochaska and DiClemente's Model) at 24 and 52 weeks after starting the treatment. | 2 years |
Countries
Canada
Outcome results
None listed