Esophageal Cancer
Conditions
Brief summary
The purpose of this study is to determine the safety and efficacy of the side-to-side stapled intrathoracic esophagogastric anastomosis in Ivor-Lewis Oesophagectomy.
Interventions
PROCEDUREside-to-side stapled esophagogastric anastomosis
20 patients of distal esophageal cancer receive side-to-side stapled esophagogastric anastomosis in Ivor-Lewis oesophagectomy
PROCEDUREcircular-stapled esophagogastric anastomosis
20 patients of distal esophageal cancer receive circular-stapled esophagogastric anastomosis in Ivor-Lewis oesophagectomy
Sponsors
Tianjin Medical University Cancer Institute and Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Cancer of the distal esophagus or gastroesophageal junction confirmed by biopsy (squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma) clinical stage I, II, or III. * Received no previous treatment for esophageal cancer * Adequate bone marrow, liver and kidney function * Patients must be able to understand the nature consent of the study and give written informed consent.
Exclusion criteria
* Age \< 18 years * History of significant heart disease * Inoperable on the basis of co-existent medical problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Long and short outcome related with anastomoses | 3 year | Include anastomotic leakage,anastomotic stricture,regurgitation,heartburn, dumping syndrome and anastomoses diameter. |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life and function outcomes | 3 year |
Countries
China
Outcome results
None listed