Athletic Performance
Conditions
Brief summary
Background of the study: Astaxanthin has been shown to be a powerfull anti-oxidant. Health benefits have been shown in animals and humans. Exercise enhancing effects have been shown in animals via enhancement of fat oxidation. We want to examine the effects of 4 weeks of astaxanthin supplementation on fat oxidation and cycling performance in trained cyclists Objective of the study: To test the hypothesis that 4 weeks supplementation with astaxanthin will improve fat oxidation and improve exercise performance in trained cyclists Study design: Double blind, placebo controlled study. Study population: Well trained cyclists between 18-30 years old Intervention (if applicable): astaxanthin (20 mg/day) or placebo for 4 weeks Primary study parameters/outcome of the study: performance on a time trial after 90 min steady state exercise. Secundary study parameters/outcome of the study (if applicable): substrate use plasma glucose plasma lactate plasma free fatty acid plasma astaxanthin Nature and extent of the burden and risks associated with participation, benefit and group relatedness (if applicable): The risks involved in participating in this experiment are minimal. Astaxanthin has been shown to be safe. Insertion of the catheters in a vein is comparable to a normal blood draw and the only risk is of a small local haematoma.
Interventions
astaxanthin
placebo
Sponsors
Study design
Eligibility
Inclusion criteria
* Healthy * Male * Age between 18 and 30 years * Endurance trained (≥3 sessions of endurance exercise per week) * VO2 max ≥ 50 ml/kg/min * Training history of more than one year of ≥3 sessions of endurance exercise per week * BMI \<25 kg/m2
Exclusion criteria
* Use of medication * Smoking
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| time trial performance | 4 weeks | time trial performance |
Secondary
| Measure | Time frame |
|---|---|
| substrate use | 4 weeks |
Countries
Netherlands