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Astaxanthin Supplementation in Cyclists

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01241877
Enrollment
24
Registered
2010-11-16
Start date
2010-11-30
Completion date
Unknown
Last updated
2011-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Athletic Performance

Brief summary

Background of the study: Astaxanthin has been shown to be a powerfull anti-oxidant. Health benefits have been shown in animals and humans. Exercise enhancing effects have been shown in animals via enhancement of fat oxidation. We want to examine the effects of 4 weeks of astaxanthin supplementation on fat oxidation and cycling performance in trained cyclists Objective of the study: To test the hypothesis that 4 weeks supplementation with astaxanthin will improve fat oxidation and improve exercise performance in trained cyclists Study design: Double blind, placebo controlled study. Study population: Well trained cyclists between 18-30 years old Intervention (if applicable): astaxanthin (20 mg/day) or placebo for 4 weeks Primary study parameters/outcome of the study: performance on a time trial after 90 min steady state exercise. Secundary study parameters/outcome of the study (if applicable): substrate use plasma glucose plasma lactate plasma free fatty acid plasma astaxanthin Nature and extent of the burden and risks associated with participation, benefit and group relatedness (if applicable): The risks involved in participating in this experiment are minimal. Astaxanthin has been shown to be safe. Insertion of the catheters in a vein is comparable to a normal blood draw and the only risk is of a small local haematoma.

Interventions

DIETARY_SUPPLEMENTastaxanthin

astaxanthin

DIETARY_SUPPLEMENTplacebo

placebo

Sponsors

Maastricht University Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy * Male * Age between 18 and 30 years * Endurance trained (≥3 sessions of endurance exercise per week) * VO2 max ≥ 50 ml/kg/min * Training history of more than one year of ≥3 sessions of endurance exercise per week * BMI \<25 kg/m2

Exclusion criteria

* Use of medication * Smoking

Design outcomes

Primary

MeasureTime frameDescription
time trial performance4 weekstime trial performance

Secondary

MeasureTime frame
substrate use4 weeks

Countries

Netherlands

Contacts

Primary ContactPeter Res, MSc
peter.res@maastrichtuniversity.nl+3143381383

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 10, 2026