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The Effect of Intravenous Magnesium Sulfate on Intraocular Pressure Following Tracheal Intubation

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01241175
Enrollment
Unknown
Registered
2010-11-16
Start date
Unknown
Completion date
Unknown
Last updated
2010-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Increased Intra Ocular Pressure (IOP)

Keywords

IOP, ophthalmic anesthesia, magnesium sulfate

Brief summary

The aim of this study is to assess the effect of preoperatively administered intra venous magnesium sulfate in attenuating pressure response to laryngoscopy and endotracheal intubation in adult patients scheduled for elective non ocular surgery

Interventions

DRUGMagnesium Sulfate
DRUGnormal saline

Sponsors

Shiraz University of Medical Sciences
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Primary purpose
PREVENTION
Masking
DOUBLE (Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 38 Years
Healthy volunteers
No

Inclusion criteria

* 18 to 38 years old * ASA I * scheduled for elective ENT ambulatory surgeries under general anesthesia

Exclusion criteria

* specific major hepatic, renal and cardio-vascular disease * known to have allergic reaction to magnesium sulphate or other drugs , -hypermagnesemia * hypocalcemia * anuria * heart block * pregnancy * any degree of renal insufficiency * digitalised patients * positive history of glaucoma or intra ocular hypertension * refused to participate

Design outcomes

Primary

MeasureTime frame
Intra ocular pressure—

Secondary

MeasureTime frame
blood pressure,heart rate—

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026