Comparison of Different Up-dosing Schedules With Osiris

Status

Terminated

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01240954

Enrollment

210

Registered

2010-11-15

Start date

2010-12-31

Completion date

Unknown

Last updated

2011-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis

Keywords

Rhinitis, Allergic, Immunotherapy

Brief summary

The purpose of this study is to compare different up-dosing schedules with Osiris.

Interventions

DRUGOSIRIS

OSIRIS current practice

DRUGOSIRIS other concentration 1

OSIRIS new concentration 1

DRUGOSIRIS other concentration 2

OSIRIS new concentration 2

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* history of grass pollen allergy * Positive SPT to grass * Positive IgE to grass

Exclusion criteria

* uncontrolled and severe asthma

Design outcomes

Primary

Measure	Time frame
evaluate the tolerability of different up-dosing schedules	30 days

Secondary

Measure	Time frame
patient's satisfaction	30 days

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026